Rifles ended the regular season in ninth place and outside the playoff bracket but take on first seed Nungua Coldstore at 15:30 GMT tonight.
Ashaiman Lions announced it will not participate in the playoffs and pulled out of the competition due to its unhappiness with league management.
The announcement has changed the scope of games with several teams pushing up the regular season standings; Ashaiman was the second seed.
After ending the regular season with just three wins in 18 games, Rifles has moved up to eighth place and set to play Coldstore.
Playing the first seed and 2016 league champions is a daunting task for the Akatsi side to progress to the next round of the three game series.
The new fixtures have Tema Heat taking on Teshie Rangers, Community 4 facing Community 2 in an all Tema affair with Francophone Stars up against Teshie Vikings.
By Yaw Adjei-Mintah
@YawMintYM on Twitter
