The tie takes place on Friday May 26 at the Prisons Court in Cantonments and is the first of two games lined up for the day and it tips off at 18:00 GMT.
Ghana Police plays DC Dynamics in the follow up game at the same venue; Police is yet to be beaten after playing four games this season while Dynamics have lost all five games.
Tema Youth has four wins in five games but the last pair of wins have attracted the attention of league followers as the wins were clinched with Youth having just five players available.
The team beat Navy Warriors 64-60 after recovering from an 11 point deficit in the final quarter with about five minutes left to play.
Tema clinched a 66-64 win over in the past round over Reformers of Prisons with the same number of players available.
Its latest matchup could prove excessively difficult since Tudu Magic leads the league.
By Yaw Adjei-Mintah
@YawMintYM on Twitter
