Two members of the elite company, Desert Rabbits and Suncity Braves will play against each other in the biggest game of the round.
Braves lead the standings with 22 points from ten wins in 12 games this season; University of Energy and Resources (UENR) and Rabbits have the same points.
A lower goal difference puts UENR in second place and Rabbits in third heading to Week 13; Braves and UENR have won the two previous editions of the league.
UENR has a slightly less challenging task against Catholic University College, Ghana (CUCG) Saints ranked seventh in the eight team league.
Barracks Scorpions play Sunyani Technical University in a mid table battle while bottom ranked side West Siders take on LIR Royals.
Royals are expected to win since West Siders have forfeited games since Week 9 due to reasons yet to be fully ascertained from the team.
By Yaw Adjei-Mintah
@YawMintYM on Twitter
