The game tips off at 18:00 GMT at the Lebanon House Court in Tudu and is the first of two games set to be played at the venue.
Defending league champions Braves of Customs take on Fire Service in the final game of the latest round of games in the division.
Navy is winless in the current campaign having lost six straight games in the first round of the season before opening the second round with a 39-75 loss to Braves.
DC is slightly better off than Navy as the Dansoman-based side has won a game which was a 62-61 win over Navy in the first round after the side battled hard from a 6-26 first quarter deficit.
A win is crucial to the fortunes of both sides as Navy can finally get in the win column for the first time this season as they try to avoid relegation while Dynamics look to build on the solitary win it has in the ongoing campaign.
By Yaw Adjei-Mintah
@YawMintYM on Twitter
